: Re: Introducing a plot-critical hallucinogen partway through a mystery? This is a sort of act related question. I have an important drug that causes the protagonist to encounter people and things
It will be very hard to write this in a way that doesn't feel like a cheat. However, in my experience as a reader, endings that feel emotionally real can get away with tying all sorts of pretzels in logic. What this means is that if the problems and challenges posed in the "drug-world" are all resolved prior to the big reveal, the book will still feel complete, whereas if the problems and challenges are solved by "oh it was all just a hallucination," people will want to toss your book out a window.
A good model is the Wizard of Oz (movie version). The entire adventure is a dream, but it has a beginning, middle and end within the dream. Dorothy can't escape her story in the middle (despite unknowingly having the means to do so), she has to complete her quest. After that, finding out it's a dream doesn't make the viewer feel cheated.
You might also make it so that the protagonist is able to gradually figure out what is happening prior to the reveal --this matches dream logic, where figuring out it's all a dream is typically the cue for the dream to end. This way he is working for his release from the drug world, rather than just getting it handed to him on a platter.
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